GCB Masthead
Center for Genetic Disorders of Cognition and Behavior
Mission Statement
The Center focuses on advancing research and clinical practice on genetic disorders associated with severe cognitive and behavioral impairment, in order to improve the quality of life for patients and families. The Centerís staff includes clinicians and scientists trained in basic and clinical neurosciences, who collaborate in multidisciplinary activities and research projects. The goal of the Center is to generate and integrate knowledge, from bench to patient, across disorders and disciplines, as well as to provide information and guidance for affected individuals and their families.

Highlighted Research Articles:

  1. Budimirovic, D.B., & Kaufmann, W.E. (2011). What Can We Learn About Autism from Studying Fragile X Syndrome? Developmental Neuroscience, 33 (5), 379-394. DOI:10.1159/000330213

  2. López-Arvizu C, Sparrow EP, Strube MJ, Slavin C, DeOleo C, James J, Hoover-Fong J, McIntosh I, Tierney E (2011) Increased symptoms of attention deficit hyperactivity disorder and major depressive disorder symptoms in nail-patella syndrome: Potential association with LMX1B loss-of-function. Am J Med Genet Part B 156: 59-66.

  3. Neul JL, Kaufmann WE, Glaze DG, Christodoulou J, Clarke AJ, Bahi-Buisson N, Leonard H, Bailey ME, Schanen NC, Kerr AM, Renieri A, Huppke P, Percy AK, for the RettSearch Consortium (2010) Rett syndrome: Revised diagnostic criteria and nomenclature. Ann Neurol 68: 944-950.

  4. Downs J, Bebbington A, Kaufmann WE, Leonard H (2010) Longitudinal hand function in Rett syndrome. J Child Neurol: Oct 4.

  5. Olmos-Serrano JL, Paluszkiewicz SM, Martin B, Kaufmann WE, Corbin JG, Huntsman MM (2010) Defective GABAergic neurotransmision and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of Fragile X Syndrome. J Neurosci 30: 9929-9938.

  6. Barnett BP, Bressler J, Chen T, Hutchins GM, Crain BJ, Kaufmann WE (2010) αB-Crystallin Negative Astrocytic Inclusions. Brain Dev: Jul 9.